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Labial melanotic macule. B). Increased numbers of me lanocytes along Download Scientific Diagram Oral pathology: Noting a pigmented macule that often presents a diagnostic dilemma Registered Dental Hygienists Oral melanotic macule Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown
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