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Development of a novel senolytic by precise disruption of FOXO4 p53 complex eBioMedicine FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI Peptide Dosing Guide: Senolytic Peptide Protocol (June 2026)

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Self-assembling peptide hydrogels as functional tools to tackle intervertebral disc degeneration

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