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In conclusion, mitophagy plays a pivotal role in cardiomyocyte hypertrophy and fibrosis, the progression of oxidative stress, inflammation, and cardiomyocyte death

Increased expression of tight junction proteins was a mechanism by which progesterone and estrogen facilitated wound healing and epithelial barrier function in intestinal epithelial cells, as reported using 2D cell lines and IBD patient-derived inflammatory organoid models (252)