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prepared LS of Clove EO by embedding casein using the freeze-thaw method and then coupled Campylobacter jejuni antibodies to the LS surface via the post-insertion method, producing protease-activated, antibacterial LS with bacterial targeting capabilities ( 6.4 Reducing the toxic effects of essential oil EOs are rarely applied directly to the skin without dilution because they may cause severe irritation

Lotito SB, Frei B (2006)

Others warn against universal supplementation because of varying treatment responses, safety concerns over long-term use, and mixed outcomes in randomized controlled trials

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