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This stage is the target of early therapeutic interventions that aim to prevent acute or delayed cell death (Paul and Candelario-Jalil, 2021

doi: 10.1186/s12896-017-0409-7 [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted] 67

There is an increasing spectrum of metabolites and neurotransmitters that are released and/or modulated by the gut microbiota in both homeostatic and pathological conditions

The previously mentioned specificity for prostate intraepithelial neoplasia allows differentiating from unmethylated benign hyperplastic prostate tissue, which always remains unmethylated