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Clinical adverse events monitoring was done on each visit and complete laboratory check-ups (both haematological and biochemical) and ECG were repeated at the end of the study (12 weeks), so as to assess the safety of the study medication

doi: 10.1128/mbio.03251-21 Summary Keywords ALS, copper, protein, aggregate, TDP-43, SOD1, C9ORF72, neurodegeneration Citation Min J-H, Sarlus H and Harris RA (2024) Copper toxicity and deficiency: the vicious cycle at the core of protein aggregation in ALS