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Use of different nicotine concentrations remained relatively stable, with 6 mg/ml being the most widely used concentration across all years

It was reported in the Plain Truth magazine that Cast-off smoke contains twice as much tar and nicotine, three times as much of a certain kind of benozopyrene (a suspected cancer agent), five times as much carbon monoxide (which robs the blood of life-giving oxygen), and 46 times as much ammonia as the smoke the smoker inhales! ( Plain Truth , New Truth About Smoking, January 1981)

The differentially expressed genes and their corresponding expression levels are listed in Supplementary Table 1

The only issue for me is the reformulated one is not as long lasting as before