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143 , 144 Rhabdomyolysis: the intense muscular activity that contributes to the production of heat also causes severe damage to the muscle tissue itself, including marked swelling and edema, loss of microscopic structural features of normal muscle, inflammatory cell infiltration, breakdown of the muscle cell membranes and leakage of the intracellular contents into the bloodstream, and finally necrosis

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GC67918 MPO-IN-1 GC36650 MPO-IN-28 MPO-IN-28 (Compound 28) is a myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM