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Dysbiosis is an imbalance in gut microbiota in which key beneficial (commensal) species become overrun by less favorable and/or more inflammatory bacteria or other microorganisms

While this needs to be verified with future research, an important implication is that patients with ME/CFS and those with fatigue in the course of long COVID should not be studied as a single group, at least until the mechanisms are better understood

Before making a final choice, consult a healthcare provider

In this review, we explore the current understanding of lipedema through clinical, tissue, and cellular lenses, and examine suspected pathological mechanisms, including hormonal influences (such as estrogen), adipocyte hypertrophy and hyperplasia, increased extracellular matrix (ECM) fibrosis, and specialized immune cell involvement, including M2 macrophage infiltration