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B12 Patches and Nasal Sprays Timeline B12 patches and nasal sprays serve as alternative systems that demonstrate possible advantages after repeated applications

NNMT inhibition as a therapeutic strategy has been explored in industry pharmaceutical pipelines (including a Pfizer program for non-alcoholic fatty liver disease that was reportedly discontinued in early clinical development), but no NNMT inhibitor has reached regulatory approval to date

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Researchers designing studies should carefully consider the evidence gap