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RCD occurs either independently of exogenous triggers or is driven by intracellular or extracellular microenvironment changes

The distribution of GR activity was analyzed, and reference intervals for serum GR were established in a single-center population in Jiangsu, Eastern China, in accordance with the guidelines of the Clinical and Laboratory Standards Institute (CLSI) C28-A3 and WS/T 402-2024 [15, 16]

Compared with chemically synthesized drugs, natural product-derived therapeutics offer significant advantages, including superior biocompatibility and functional diversity, attributes shaped by evolutionary optimization through long-term natural selection (Yao et al., 2017)

Of particular interest in geroscience, some abundant cellular ncRNAs, such as microRNAs (miRNAs), might play understudied functions that are central in controlling signaling dynamics