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However, additional data was gathered with the knockout mice that indicated that while AOD9604 did not lead to significant weight loss or increase in lipolysis without the beta(3)-adrenergic receptors, there was an increase in energy expenditure and fat oxidation

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In addition, B-12 shots reduce the risk of some serious complications associated with vitamin B-12 deficiency including: Heart disease Neurocognitive disorders Coordination problems (ataxia) Peripheral nephropathy Vision loss Infertility (although this usually resolves with B-12 treatment) Neural tube defects in the babies of women with B-12 deficiency