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Hitting the Right Spot: Advances in the Treatment of NSCLC With Uncommon EGFR Mutations

AtGLXI.1 and AtGLXI.2 display a higher activity with Ni 2+ using MG and GSH as substrates whereas Mn 2+ is preferred for the conversion of GO and GSH

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Direct effects of ROS, generally attributed to high concentrations at the site of damage, include DNA strand breaks, point mutations, aberrant DNA cross-linking, and mutations in proto-oncogenes and tumor-suppressor genes, thus promoting neoplastic transformation [7, 95]