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Additionally, we have found that schistosomes do not have either an authentic glutathione disulfide reductase (GR) or thioredoxin reductase (TrxR) enzymes

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Curcumin also enhances the production of microbial metabolites, particularly short-chain fatty acids (SCFAs) such as butyrate, which exert systemic anti-inflammatory and neuroprotective effects by modulating microglial activation and tight junction protein expression in the gut epithelium [46,49]

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