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Ziegler L Article: METABOLISM-CLINICAL AND EXPERIMENTAL

Enzymatic degradation by proteases and chemical instability can limit therapeutic effectiveness and require specialized storage and handling procedures

Interestingly, several consensus sites for PAD have been identified in RG/RGG motifs

This theory matches data from the German prospective multicenter study ALLIVE including 22 MDS and 90 AML patients and some smaller studies, which show an increase in NTBI and LIP levels during allogeneic HSCT ( During the course of AML, signs of iron overload have also been described