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So-called senolytic drugs, are compounds that are effective both in vitro and in vivo, in targeting and eliminating senescent cells 4

Tous les trois sont laurats du Prix Nobel de Chimie : Todd en 1957, Hodgkin en 1964, et Woodward en 1965 [6]

The target sequence GTGTCAGGAGGTGTTTGGAAAG (SEQ ID NO: 2) was inserted into pSUPER vector (Oligoengine, Seattle WA) which drives endogenous production of shRNA under the HI promoter