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According to a peer-reviewed study published in PLOS ONE confirming that Semax affects the expression of genes related to the neurotrophin signaling pathway, specifically upregulating BDNF in the hippocampus, Semax significantly increases BDNF and its receptor TrkB in the rat hippocampus, with effects on both memory and neuronal resilience

P.FujiwaraT.HayashiH.YoneyamaT.et al (2002)

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