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Raw WRS values were then normalized by z-scoring relative to the cohort median and displayed in a waterfall plot (Fig

STAT3 and CREB coordinate the hyperaminoacidemia-induced VGF upregulation To elucidate the mechanism of glutamine and alanine-induced VGF upregulation in cells, we used the databases including AnimalTFDB 26 , GTRD 27 , and TFBIND 28 to predict the transcription factors that could bind to the VGF promoter