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Opioid withdrawal induces oxidative stress and disrupts glutamate and glutathione homeostasis

Pseudoephedrine is largely excreted unchanged by the kidneys

In A1-42-induced HT-22 cells, ERD (2, 4, and 8 M) significantly enhanced cell survival, reduced Tau hyperphosphorylation and neurotoxicity, and decreased lipid ROS and iron levels, highlighting its neuroprotective potential (Li L