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While both are amphetamines, Dexedrines pure dextroamphetamine composition makes it more targeted, whereas Adderalls combination offers a broader spectrum of effects

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Acetazolamide is the first-line of prophylaxis, FDA approved drug for AMS that works at the level of kidneys and causes bicarbonate diuresis and metabolic acidosis, promoting ventilatory acclimatization to hypoxia 25