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Because arthrocentesis interacts with a wide clinical range of musculoskeletal and rheumatologic conditions, proper bundling review is essential to ensure compliance

Weight changes Weight effects are the slowest and least predictable

These may include: muscle relaxants, narcotics, pain medications (NSAIDs), antihypertensives, antiarrhythmics, diuretics, drugs that speed up gut motility, antibiotics, antidepressants, and others

If folate deficiency is suspected, it is reasonable to give oral folic acid (0.4 1 mg/day) without doing laboratory investigation for deficiency at least until the hemoglobin and mean corpuscular volume normalizes (or longer if the underlying cause cannot be eliminated)