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Cystine can enter the lysosomes via cystine-containing proteins or enter the cell via apical membrane transporters

In the central nervous system, ammonia can cross the bloodbrain barrier and is normally detoxified by astrocytic glutamine synthetase, but whether brain metastatic tumor cells exploit or tolerate this ammonia-rich environment remains unclear ( From a clinical-translational perspective, elevated ammonia is not merely a metabolic byproduct but actively drives immune evasion and therapeutic resistance

Eat More Selenium-Rich Foods Selenium is an essential mineral that works closely alongside glutathione and supports the activity of glutathione-dependent enzymes within the body

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