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29 31 Under hypoxia, mitochondrial respiration generates increased ROS, reasoning the diversion of pyruvate away from the TCA cycle, but perhaps another crucial advantage of metabolizing pyruvate through the lactate axis instead is the inherent need for the regeneration of co-factor nicotinamide adenine dinucleotide (NAD) + in order to sustain a continued high glycolytic flux

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Hormone-sensitive conditions Breast cancer history: Consult oncologist before GH peptides Estrogen-related concerns BPC-157, GHK-Cu generally safe Individual assessment needed Uterine fibroids: GH peptides may affect (theoretical) Monitor if using BPC-157 safe Weight loss peptides safe Thyroid issues: Common in women 40+ Peptides generally compatible with thyroid meds Monitor thyroid function Some peptides may help thyroid Combining with HRT/bioidentical hormones Can you use both peptides and HRT

10.1155/2016/7961816 136 LiD.WangG