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Statements Data availability statement The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to [email protected], [email protected]

This disruption severely impairs ATP synthesis in cardiomyocytes, leading to energy depletion

Remarkably, recent evidence demonstrated impairment of mitochondrial degradation in glomerular and tubular cells was implicated in proteinuria and renal failure in LN (89, 90)