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Clinical, Cosmetic and Investigational Dermatology, 2014

The skin-specific mechanisms of GHK-Cu include stimulation of Type I and Type III procollagen synthesis, increased production of dermatan sulfate and other glycosaminoglycans, activation of the enzyme lysyl oxidase (which cross-links newly formed collagen), reduction of matrix metalloproteinase-1 (MMP-1, collagenase) activity, and anti-inflammatory suppression of TNF-alpha-induced IL-6 secretion

For the researcher who has been quantifying cysteine by HPLC with dual electrochemical detectiona method that delivers precision but requires a dedicated chromatography system, per-sample run times exceeding 20 minutes, and operator training that most metabolism laboratories do not possessthe shift from HPLC to microplate-based colorimetric detection is not a compromise

This episode is a direct challenge to that narrative