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Endocrine Metab Immune Disord Drug Targets (2019) 19:30815

In summary, while the reviewed clinical studies provide encouraging signals, they suffer from small samples, heterogeneous populations, non-standardized endpoints, and short durations

In AA, they diminish perifollicular inflammatory infiltrates (e.g., CD3 and CD8 + T cells) and suppress key immune mediators such as IL-2, IL-15, and IFN- [107,108,109]