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Thymosin Alpha-1, for example, has a plasma half-life of approximately 2 hours but exerts immunomodulatory effects for considerably longer periods, likely because of downstream signaling cascades that persist well beyond peptide clearance

Rats were performed in vivo fluorescence imaging at specified time points post-administration using an In Vivo Imaging System (Newton, Viber Bio Imaging, France)

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Am J Psychiatry (2004) 161:1698700.10.1176/appi.ajp.161.9.1698 54 GreenEKRaybouldRMacgregorSHydeSYoungAHODonovanMCet alGenetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK