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2015 May 8;16(5):10624-35

There is no complex cycling pattern

Dihexa, with its combined N-hexanoic-Tyr-Ile-(6) aminohexanoic amide structure, exhibited a significantly extended half-life of 335.5 9.5 min, confirming that both N- and C-terminal modifications are effective strategies for improving metabolic stability [1]

First-line interventions such as sedative-hypnotics, melatonin agonists, and CBT-I (Cognitive Behavioral Therapy for Insomnia) have limited long-term efficacy