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In high-altitude regions, Lactobacillus plantarum S27 has been proposed as a potential alternative to antibiotics in bird feed ( in vitro studies have demonstrated that Lactobacillus acidophilus DDS-1 can enhance mucosal barrier function by upregulating mucin gene expression and promoting mucin secretion from intestinal epithelial cells, while simultaneously secreting antimicrobial peptides (Mack et al., 2003)