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The institution where you are practicing will likely have some basic guidelines on initiating warfarin, so when in doubt use those

BMC Plant Biol 9:130

Sodium bicarbonate should be used if the pH is below 7.2 (molar bicarbonate infusion via venous a catheter at a dose of 1 to 3 mEq/kg)

The trial methodology may not always meet the gold-standard requirements of Western regulatory agencies, but the breadth and consistency of positive findings across multiple studies provides meaningful confidence in its efficacy and safety