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Autoxidation of NO with oxygen results in the formation of nitrite, a substrate for eosinophil peroxidase (EPO) and myeloperoxidase (MPO) [25]

Regardless of your skin sensitivity level, it's always a good idea to do a patch test by rubbing a little bit of the lubricant on your thigh or other skin to see if you have any reactions before you start using it on your most sensitive body parts