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In the CY 2025 PFS proposed rule (89 FR 62238, 62247, and 62248) and this final rule, we have described ( the criteria that must be satisfied for CMS to grant a rebate reduction request

Boosting with 2P-S-encoding mRNA vaccines has been shown to focus the humoral response on prefusion epitopes, resulting in higher and broader nAb responses [163]

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