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Cell assays show SLU-PP-332 activates all three ERR isoforms but is roughly four-fold more potent at ERR than ERR , with ERR in between (ERR EC50 98 nM, ERR EC50 430 nM)

It also serves as a carrier for copper, an essential cofactor for critical antioxidant enzymes like superoxide dismutase (SOD1)

Official FDA / NIH Drug Monograph (Primary Source) Bacteriostatic Water for Injection, USP This official NIH-hosted drug monograph confirms: Bacteriostatic Water is a sterile, non-pyrogenic preparation Contains 0.9% benzyl alcohol as a bacteriostatic preservative Supplied in multi-dose containers Designed for repeated withdrawals to dilute or dissolve drugs for injection Multi-Dose Pharmaceutical Preparation Research Bacteriostatic Water for Injection (bWFI) in Parenteral Products This formulation research outlines that: bWFI is commonly used in parenteral pharmaceutical preparation Prepared using antimicrobial agents such as benzyl alcohol These preservatives are included to suppress the growth of microbial contaminants Antimicrobial Preservatives in Peptide Formulations Antimicrobial Preservatives for Protein and Peptide Formulations This review discusses: The necessity of antimicrobial preservatives Compatibility of preservatives with peptide compounds Use of benzyl alcohol in multi-dose biologic formulations Stability considerations in peptide reconstitution systems Highly relevant for: Lyophilised peptide storage Multi-withdrawal vial integrity Laboratory reconstitution environments For research purposes only

Subjects had to be over 15 years of age, present with soot in the mouth and expectoration (to indicate significant smoke exposure), and have altered neurological status