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The Timeless Takeaways From Powers and colleagues, we gain lessons that remain fresh even 25 years later: Exercise is hormesis

(2012), in their study, reported that 22 out of 33 male patients with severe idiopathic oligoasthenoteratozoospermia (OAT) of infertile couples whose partners had undergone at least one ICSI cycle, showed reduced sperm aneuploidy levels (assessed using fluorescent in situ hybridization performed on chromosomes X, Y, 13, 15, 16, 17, 18, 21 and 22) and improved sperm morphology after 3 months of treatment with LC 2 1 g/day, ALC 2 500 mg/day and cinnoxicam (a lipophilic NSAID) 1 30 mg/every 4 days [89]

PMID: 38674069, PMCID: PMC11050327, DOI: 10.3390/ijms25084484

Consistent with this, overexpression of RIPK3 in white adipose tissue (WAT) of mice and humans mitigates adipocyte apoptosis and inflammation, preserving insulin signaling and glucose tolerance [11]