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Phenotypic and functional characteristics of murine CD11c + B cells which is suppressed by metformin

To assess p53 expression, flow cytometric analysis was carried out on live cells, and GFP expression was monitored using the FITC channel on a BD LSRII

The TME encompasses numerous immunosuppressive cell types, such as cancer-associated fibroblasts (CAFs), TAMs, myeloid-derived suppressor cells (MDSCs) and Foxp3 + regulatory CD4 + T cells (Tregs)