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Use of genetic variants to predict clinical outcome in patients (pts) with metastatic colorectal cancer (mCRC) treated with first-line 5-FU or capecitabine in combination with oxaliplatin and bevacizumab (FOLFOX/BV or XELOX/BV)

doi: 10.1038/nature11984 118 XiaB

ADAP1 and Arf6 mediate regulated secretory trafficing in neurosecretory cells and neurons

It is a major source of morbidity and mortality worldwide, with an estimated 12 million new cases occurring annually, with an increasing incidence due to aging populations and associated risk factors such as hypertension, diabetes, and smoking (An et al