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Botulinum neurotoxin type A (BoNT/A), an exotoxin from Clostridium botulinum, reversed the downregulation of type II collagen and the upregulation of MMP-13 induced by LPS in chondrocytes, alleviating LPS-induced chondrocyte toxicity, activating the SLC7A11/GPX4 antiferroptotic system, and enhancing mitochondrial function

Methods : This is an ecological study analyzing hospitalizations due to diabetic foot complications in Brazil from January 2014 to December 2024, as well as their associated total cost

Immune cells use glutathione both as an antioxidant and as a signaling molecule that helps coordinate your bodys defense responses

Acknowledgements We thank all researchers and clinicians for their contributions to the field and apologize to those whose work we did not describe or cite