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It works by activating melanocortin receptors in the brain, which are responsible for regulating sexual behavior in both sexes

10.11648/j.ijpc.20170306.12 96 KhanM

However, we focus on the effect of GHK on astrocytes only, rather than the interaction with neurons

This results in decreased expression of the articulin CD2AP and the podocyte cytoskeleton protein synaptopodin, while increased expression of the transcription factor snail and nerphrin, a marker protein of podocyte injury, ultimately leads to podocyte actin skeleton remodeling and cell migration[94]