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Conclusion While preliminary findings highlight the promise of PRP and PRGF as emerging, plasma-based approaches in male reproductive medicine, further research is essential to standardize protocols, evaluate long-term efficacy and safety, and elucidate underlying molecular mechanisms before these therapies can be safely and effectively translated into routine clinical practice

Therefore, combining the induction of tumor cell ferroptosis with immunotherapy presents significant potential for clinical application in cancer therapy ( Table 1 )