glutathione depletion paracetamol Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential Ferroptosis and Intrinsic Drug-induced Liver

In recent years, oxidative stress has been recognized as one of the main pathomechanisms of AD, since this phenomenon is closely related to some key events in neurodegeneration, such as mitochondrial dysfunction, inflammation, metal-induced toxicity, and protein misfolding (Nunomura and Perry 2020)

Med Cent.) 13 , 421423 (2000)

Mechanistically, it influences gene networks involved in tissue remodeling and exerts protective antioxidant and anti-inflammatory actions, partly through TGF- signaling and regulation of metalloproteinases

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