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Diagnosis The diagnosis of PFIC is based on a combination of clinical data and laboratory or biochemical results, radiologic and histological evaluations if needed [13], with the crucial support of genetic testing [2]

But then there are others that, in the United States, currently drift in a state of legal limbo

That is, a reasonable target at one time point during development may be inappropriate at another time point because of structural and functional changes based on neuronal migration, circuit connectivity, synaptic plasticity, and gene expression

This protection is crucial for maintaining the skin's integrity and youthful appearance