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Approaches for enhancing oral bioavailability of peptides and proteins

(v) Molecularly targeted nanoparticles irradiated by picosecond pulsed laser to reversibly open the BBB and deliver drugs to brain tissue, specifically by synthesizing a gold nanoparticles (AuNPs) that are specifically targeted intravenously to tight junctions (TJs) on the BBB, followed by cranial picosecond laser stimulation to increase BBB permeability, a strategy that allows immunoglobulin and viral gene therapy vectors and drug-laden liposomes to enter the brain, and a process that is reversible and does not result in spontaneous vascular diastole or significant disruption of the structure of the neurovascular unit ( TABLE 2 Advantages and disadvantages of drug delivery methods

In dermographic urticaria H2 receptor antagonists have a small but therapeutically irrelevant additional effect compared with H1 antagonists alone

Blood superoxide dismutase (SOD) activity was assyed according to the method of Marklund and Marklund [53]