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SKU: 89573598907
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SKU: 89573598907 · From www.djecji-vrtic-kucica.hr

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The phenotypic hallmark of the SOD1-dependent ALS is the presence of amyloid aggregates of SOD1 in affected tissues, which are the ultimate outcome of SOD1 misfolding the product of a gradual destabilization of the SOD1 structure due to the loss of metal ions and the reduction of the stabilizing intrasubunit disulfide bond 10,11,12

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