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Halpin SJ, Hamlin PJ, Greer DP, Warren L, Ford AC

Abatacept (ABT) is a co-stimulation inhibitor that can bind to CD80 and CD86, preventing CD28-mediated T cell activation by blocking costimulatory signaling

DOI: 10.1146/annurev.bi.55.070186.005303 Hollenberg, S.M., Weinberger, C., Ong, E.S., Cerelli, G., Oro, A., Lebo, R., Thompson, E.B., Rosenfeld, M.G., Evans, R.M