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Inflammaging is associated with increased susceptibility to infections, autoimmune disorders and various age-related diseases, creating a feedback loop that accelerates the breakdown of immune health and increases morbidity and mortality risks among elderly [3, 4]

Unlike its DAC counterpart, CJC-1295 No DAC does not contain a drug affinity complex, which results in a shorter half-life

From a genetic perspective, some genes such as APOE4 and oligoadenylate synthetase 1 (OAS1) play important roles in susceptibility to both COVID-19 and AD

However, there still lacks direct and effective therapeutic interventions to alleviate cisplatin-induced AKI (Cis-AKI) [7]