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Although several environmental agents are implicated in the pathogenesis of ADs via numerous mechanisms, below we discuss the more prominent ones which are not only known to induce/exacerbate autoimmunity but also have oxidative stress (OS) as one common mechanism, and participate in the pathogenesis of ADs (Figure 1): Figure 1 Mercury Mercury (Hg) is a well-established environmental toxicant and its exposure in humans is associated with markers of inflammation and autoimmunity ( In vivo studies using autoimmune-prone murine models report that exposure to inorganic Hg leads to lupus-like syndrome

Combined with the drug, these beneficial results were consistently observed across all tested glycating and oxidizing agents (Figs

MicroRNAs mediated regulation of glutathione peroxidase 7 expression and its changes during adipogenesis

Hopkins, R