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47 143183 10.1146/annurev.pharmtox.47.120505.105122 [DOI] [PubMed] [Google Scholar] Osenkowski P., Ye W., Wang R., Wolfe M

Cell 186 (13), 27482764.e22

HBV breakpoints resulting in HBV-DNA integration most commonly localize within a 1,800 bp region of the HBV genome, preserving the structural integrity of the envelope, X and polymerase open reading frames [4]