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10.1007/s10068-010-0110-2 321

Desmaris et al., 2018)

At the same time, calcium overload promotes the decomposition of complex II in the respiratory chain by binding to cardiolipin in the inner mitochondrial membrane (IMM), leading to the release of various subunits, resulting in the production of large amounts of reactive oxygen species (ROS) and ultimately causing cell apoptosis [92]