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Might be helpful for skin lightening Might help improve cell turnover and reduce inflammation in skin

TNF- levels decreased in the HF12 + AVO and HF6+AVO groups with respect to the levels of the HF12 and HF6 groups, respectively

J Clin Endocrinol Metab 59:2933 Pasqualini JR, Chetrite G, Blacker D, Feinstein MC, Delalonde L, Talbi M, Maloche C (1996) Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and post-menopausal breast cancer patients

Phosphorylation of eIF2 by PERK in response to ER stress decreases translation of mRNA and reduces stress (Harding et al , 2003)