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What the 28-day window requires: The clock starts at first puncture, not at the date printed on the vial

(1990) Am J Physiol 259:G524-G529

L-Citrulline can be synthesized in the body as an intermediate in the conversion of orthinine to arginine in the urea cycle, it is also produced from arginine as a byproduct of the reaction catalyzed by the enzyme NO synthase